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Article

Dual-Genotype Diffuse Low-Grade Glioma: Is It Really Time to Abandon Oligoastrocytoma As a Distinct Entity?

Journal of neuropathology and experimental neurology - 1 May 2017

Barresi Valeria, Lionti Simona, Valori Laura, Gallina Giovanna, Caffo Maria, Rossi Sabrina

Abstract excerpt

We report a unique case of dual-genotype oligoastrocytoma characterized by IDH2 gene mutation. The tumor was resected from the temporal lobe of a 25-year-old man. At histological examination with hematoxylin and eosin stain, it showed distinct oligodendroglial and astrocytic areas. The former retained alpha-thalassaemia/mental retardation X-linked (ATRX) immuno-expression and had absent staining for p53, while...

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Source

Identifiers

PMID: 28419269
DOI: 10.1093/jnen/nlx024

Genes

ATRX
IDH2
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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