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Article

Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus.

Molecular carcinogenesis - 1 May 2016

Lieberman Rachel, Xiong Donghai, James Michael, Han Younghun, Amos Christopher I, Wang Liang, You Ming

Abstract excerpt

Recent genome-wide association studies have identified variations in the recombination repair gene, RAD52, that are associated with increased lung cancer risk, and particularly with the development of lung squamous cell carcinomas (LUSC). As LUSC development is strongly associated with smoking, DNA repair is increased in the lung tissues of smokers, presumably because of ongoing DNA damage from exposure to...

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Source

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Identifiers

PMID: 26013599
DOI: 10.1002/mc.22334
PMCID: PMC4662629

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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