Article
Altered Microglia in the Amygdala Are Involved in Anxiety-related Behaviors of a Copy Number Variation Mouse Model of Autism.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi - 1 Jan 2015
Shigemori Tomoko, Sakai Atsushi, Takumi Toru, Itoh Yasuhiko, Suzuki Hidenori
Abstract excerpt
BACKGROUND AND PURPOSE: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic basis. Although anxiety is a common major psychiatric condition in ASD, the underlying mechanisms of the anxiety are poorly understood. In individuals with ASD, evidence indicates a struc...
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