Article

Elevated gene expression of most microglial markers, and reduced expression of most pyramidal neuron and interneuron markers, in postmortem autism cortex

2015-11-21

Abstract excerpt

Autism Spectrum Disorders (ASD) are clinically and genetically heterogeneous. Nevertheless, a characteristic gene expression signature in postmortem cortex is shared across most ASD cases. Knowing whether this signature reflects changes in cells of particular types would help to determine the molecular, cellular, and anatomical etiology of ASD. To investigate we took advantage of cell type marker genes defined by...

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Literature Corpus work: 2eccff6f-1f8a-5980-9921-48ece3e3958c
DOI: 10.1101/032557

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