Article

Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism

2017-09-23

Abstract excerpt

Dysregulation in immune responses during pregnancy increase the risk of a having a child with an autism spectrum disorder (ASD). Asthma is one of the most common chronic diseases among pregnant women, and symptoms often worsen during pregnancy. We recently developed a mouse model of maternal allergic asthma (MAA) that induces changes in sociability, repetitive and perseverative behaviors in the offspring. Since ep...

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Literature Corpus work: 411c640c-f16d-5251-9a72-c9282d9c6ed6
DOI: 10.1101/192997

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