Article
Negative and positive temperature dependence of potassium leak in MscS mutants: Implications for understanding thermosensitive channels.
Biochimica et biophysica acta - 1 Aug 2015
Koprowski Piotr, Sliwinska Malgorzata A, Kubalski Andrzej
Abstract excerpt
Bacterial mechanosensitive channel of small conductance (MscS) is a protein, whose activity is modulated by membrane tension, voltage and cytoplasmic crowding. MscS is a homoheptamer and each monomer consists of three transmembrane helices (TM1-3). Hydrophobic pore of the channel is made of TM3s...
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