Article
Ionic regulation of MscK, a mechanosensitive channel from Escherichia coli.
The EMBO journal - 15 Oct 2002
Li Yuezhou, Moe Paul C, Chandrasekaran Subramanian, Booth Ian R, Blount Paul
Abstract excerpt
Three gene products that form independent mechanosensitive channel activities have been identified in Escherichia coli. Two of these, MscL and MscS, play a vital role in allowing the cell to survive acute hypotonic stress. Much less is known of the third protein, MscK (KefA). Here, we characterize the MscK channel activity and compare it with the activity of its structural and functional homologue, MscS. While...
Topics
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- Ion Channel Gating
- Ion Channels
- Mechanotransduction, Cellular
- Mutation
- Phenotype
- Potassium
- Sodium