Article
The evolutionary 'tinkering' of MscS-like channels: generation of structural and functional diversity.
Pflugers Archiv : European journal of physiology - 1 Jan 2015
Cox C D, Nakayama Y, Nomura T, Martinac B
Abstract excerpt
The mechanosensitive channel of small conductance (MscS)-like channel superfamily is present in cell-walled organisms throughout all domains of life (Bacteria, Archaea and Eukarya). In bacteria, members of this channel family play an integral role in the protection of cells against acute downward shifts in environmental osmolarity. In this review, we discuss how evolutionary 'tinkering' has taken MscS-like...
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