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Article

Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK.

Molecular microbiology - 1 Apr 2007

Li Chan, Edwards Michelle D, Jeong Hotcherl, Jeong Hochterl, Roth John, Booth Ian R

Abstract excerpt

Mechanosensitive channels allow bacteria to survive rapid increases in turgor pressure. Substantial questions remain as to how these channels sense and respond to mechanical stress. Here we describe a set of mutants with alterations in their MscK channel protein. The mutants were detected fortuitously by their enhanced ability to modify the accumulation of quinolinic acid. Some amino acid changes lie in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17493135
DOI: 10.1111/j.1365-2958.2007.05672.x
PMCID: PMC1890815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK.PMID 17493135Read ↗

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