Article
Mutations in a Conserved Domain of E. coli MscS to the Most Conserved Superfamily Residue Leads to Kinetic Changes.
PloS one - 1 Jan 2015
Malcolm Hannah R, Blount Paul
Abstract excerpt
In Escherichia coli (E. coli) the mechanosensitive channel of small conductance, MscS, gates in response to membrane tension created from acute external hypoosmotic shock, thus rescuing the bacterium from cell lysis. E. coli MscS is the most well studied member of the MscS superfamily of channels, whose members are found throughout the bacterial and plant kingdoms. Homology to the pore lining helix and upper...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.