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Article

The cytoplasmic cage domain of the mechanosensitive channel MscS is a sensor of macromolecular crowding.

The Journal of general physiology - 1 May 2014

Rowe Ian, Anishkin Andriy, Kamaraju Kishore, Yoshimura Kenjiro, Sukharev Sergei

Abstract excerpt

Cells actively regulate the macromolecular excluded volume of the cytoplasm to maintain the reciprocal fraction of free aqueous solution that is optimal for intracellular processes. However, the mechanisms whereby cells sense this critical parameter remain unclear. The mechanosensitive channel of small conductance (MscS channel), which is the major regulator of turgor in bacteria, mediates efflux of small...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24778428
DOI: 10.1085/jgp.201311114
PMCID: PMC4003192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The cytoplasmic cage domain of the mechanosensitive channel MscS is a sensor of macromolecular crowding.PMID 24778428Read ↗

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