Article
CYP2D6 genotype and phenotype determination in a Mexican Mestizo population.
European journal of clinical pharmacology - 1 Nov 2005
López Marisol, Guerrero Jorge, Jung-Cook Helgi, Alonso María Elisa
Abstract excerpt
OBJECTIVE: Although CYP2D6 genetic polymorphism plays an important role in interindividual and interethnic variability in drug response, very few pharmacogenetic data are available from Hispanic populations, including Mexicans. For this purpose, this study was undertaken to determine CYP2D6 genotype and phenotype in a healthy Mexican Mestizo population. METHODS: Genotyping of five CYP2D6 mutant alleles by...
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