Article
High prevalence of CYP2D6 ultrarapid metabolizers in a mestizo Colombian population in relation to Hispanic mestizo populations.
Pharmacogenomics - 1 Nov 2020
P Sarmiento Alba, Dorado Pedro, Borbón Angélica, de Andrés Fernando, LLerena Adrián
Abstract excerpt
Background: Interethnic differences in CYP2D6 allele frequency have been demonstrated across Latin-American countries. Only one previous study describing CYP2D6 genotypes in Colombian population has been performed. Thus, this study aimed to evaluate the CYP2D6 genetic variability in a mestizo Colombian population, as well as the similarities and differences concerning other Hispanic mestizo (HM) populations....
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