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Article

Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers.

European journal of clinical pharmacology - 1 Jun 2015

Christensen Mette Marie Hougaard, Højlund Kurt, Hother-Nielsen Ole, Stage Tore Bjerregaard, Damkier Per, Beck-Nielsen Henning, Brøsen Kim

Abstract excerpt

PURPOSE: The aim of the study was to determine the steady-state pharmacokinetics of metformin in healthy volunteers with different numbers of reduced-function alleles in the organic cation transporter 1 gene (OCT1). METHODS: The study was conducted as part of a randomized cross-over trial. Thirty...

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Identifiers

PMID: 25939711
DOI: 10.1007/s00228-015-1853-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25939711-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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