Article
Drosophila DBT Autophosphorylation of Its C-Terminal Domain Antagonized by SPAG and Involved in UV-Induced Apoptosis.
Molecular and cellular biology - 1 Jul 2015
Fan Jin-Yuan, Means John C, Bjes Edward S, Price Jeffrey L
Abstract excerpt
Drosophila DBT and vertebrate CKIε/δ phosphorylate the period protein (PER) to produce circadian rhythms. While the C termini of these orthologs are not conserved in amino acid sequence, they inhibit activity and become autophosphorylated in the fly and vertebrate kinases. Here, sites of C-termin...
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