Article
Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population.
Arthritis research & therapy - 18 Apr 2015
Terao Chikashi, Ohmura Koichiro, Kochi Yuta, Ikari Katsunori, Okada Yukinori, Shimizu Masakazu, Nishina Naoshi, Suzuki Akari, Myouzen Keiko, Kawaguchi Takahisa, Takahashi Meiko, Takasugi Kiyoshi, Murasawa Akira, Mizuki Shinichi, Iwahashi Mitsuhiro, Funahashi Keiko, Natsumeda Masamitsu, Furu Moritoshi, Hashimoto Motomu, Ito Hiromu, Fujii Takao, Ezawa Kazuhiko, Matsubara Tsukasa, Takeuchi Tsutomu, Kubo Michiaki, Yamada Ryo, Taniguchi Atsuo, Yamanaka Hisashi, Momohara Shigeki, Yamamoto Kazuhiko, Mimori Tsuneyo, Matsuda Fumihiko
Abstract excerpt
INTRODUCTION: Although susceptibility genes for anti-citrullinated peptide/protein antibodies (ACPA)-positive rheumatoid arthritis (RA) have been successfully discovered by genome-wide association studies (GWAS), little is known about the genetic background of ACPA-negative RA. We intended to elucidate genetic background of ACPA-negative RA. METHOD: We performed a meta-analysis of GWAS comprising 670...
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