Article
New insights into the genetics of immune responses in rheumatoid arthritis.
Tissue antigens - 1 Aug 2012
Ruyssen-Witrand A, Constantin A, Cambon-Thomsen A, Thomsen M
Abstract excerpt
Rheumatoid arthritis (RA) is a common autoimmune disease with a strong genetic component. Numerous aberrant immune responses have been described during the evolution of the disease. In later years, the appearance of anti-citrullinated protein antibodies (ACPAs) has become a hallmark for the diagnosis and prognosis of RA. The post-translational transformation of arginine residues of proteins and peptides into...
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