Effects of Human Leukocyte Antigen DRB1 Genetic Polymorphism on Anti-Cyclic Citrullinated Peptide (ANTI-CCP) and Rheumatoid Factor (RF) Expression in Rheumatoid Arthritis (RA) Patients.

doi:10.3390/ijms241512036

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Effects of Human Leukocyte Antigen DRB1 Genetic Polymorphism on Anti-Cyclic Citrullinated Peptide (ANTI-CCP) and Rheumatoid Factor (RF) Expression in Rheumatoid Arthritis (RA) Patients.

International journal of molecular sciences - 27 Jul 2023

Chen Yu-Chia, Huang Chung-Ming, Liu Ting-Yuan, Wu Ning, Chan Chia-Jung, Shih Peng-Yu, Chen Hsin-Han, Chen Shih-Yin, Tsai Fuu-Jen

Abstract excerpt

Rheumatoid arthritis (RA) is a systemic disease characterized by non-infectious inflammation of the joints and surrounding tissues, which can cause severe health problems, affect the patient's daily life, and even cause death. RA can be clinically diagnosed by the occurrence of blood serological markers, rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (anti-CCP). However, about 20% of RA...

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PMID: 37569411
DOI: 10.3390/ijms241512036
PMCID: PMC10418683

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