Article
Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Jul 2016
Viatte Sebastien, Massey Jonathan, Bowes John, Duffus Kate, Eyre Stephen, Barton Anne, Worthington Jane
Abstract excerpt
OBJECTIVE: Genetic polymorphisms within the HLA region explain only a modest proportion of anti-cyclic citrullinated peptide (anti-CCP)-negative rheumatoid arthritis (RA) heritability. However, few non-HLA markers have been identified so far. This study was undertaken to replicate the associations of anti-CCP-negative RA with non-HLA genetic polymorphisms demonstrated in a previous study. METHODS: The Rheumatoid...
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