Article
A replication study confirms the association of dendritic cell immunoreceptor (DCIR) polymorphisms with ACPA - negative RA in a large Asian cohort.
PloS one - 1 Jan 2012
Guo Jianping, Wu Xinyu, Too Chun Lai, Yin Fangrui, Lu Xiaolan, He Jing, Li Ru, Liu Xu, Murad Shahnaz, Padyukov Leonid, Li Zhanguo
Abstract excerpt
OBJECTIVES: Dendritic cell immunoreceptor (DCIR) has been implicated in development of autoimmune disorders in rodent and DCIR polymorphisms were associated with anti-citrullinated proteins antibodies (ACPA)-negative rheumatoid arthritis (RA) in Swedish Caucasians. This study was undertaken to further investigate whether DCIR polymorphisms are also risk factors for the development of RA in four Asian populations...
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