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Article

[Mutation screening and function prediction of melanocortin-4 receptor gene in obese children].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Apr 2015

Song Jie-Yun, Wang Du, Ma Jun, Wang Hai-Jun

Abstract excerpt

OBJECTIVE: To screen the coding region of melanocortin-4 receptor gene (MC4R) for mutations in children, analyze the association of the identified variants with obesity-related phenotypes, and predict the potential functions of the identified variants. METHODS: A case-control study was conducted in 160 severely obese children and 100 normal-weight controls, all aged 7-18 years. Their anthropometric data were...

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PMID: 25919555

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