Article
Association of a variant in the regulatory region of NADPH oxidase 4 gene and metabolic syndrome in patients with chronic hepatitis C.
European journal of medical research - 28 Mar 2015
Siqueira Erika Rabelo Forte de, Pereira Luciano Beltrao, Stefano Jose Tadeu, Patente Thiago, Cavaleiro Ana Mercedes, Silva Vasconcelos Luydson Richardson, Carmo Rodrigo Feliciano, Moreira Beltrao Pereira Leila Maria, Carrilho Flair Jose, Corrêa-Giannella Maria Lucia, Oliveira Claudia P
Abstract excerpt
BACKGROUND: Given the important contribution of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system to the generation of reactive oxygen species induced by hepatitis C virus (HCV), we investigated two single nucleotide polymorphisms (SNPs) in the putative regulatory region of the genes encoding NADPH oxidase 4 catalytic subunit (NOX4) and its regulatory subunit p22phox (CYBA) and their relation...
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