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Article

Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Aug 2018

Rabelo Fabiola, Stefano Jose Tadeu, Cavaleiro Ana Mercedes, Lima Rodrigo Vieira Costa, de Campos Mazo Daniel Ferraz, Carrilho Flair Jose, Correa-Giannella Maria Lúcia, Oliveira Claudia P

Abstract excerpt

BACKGROUND: Oxidative stress has been implicated in the progression of severe forms of non-alcoholic fatty liver disease (NAFLD). NADPH oxidase produces reactive oxygen species. In the present study, we investigated for the first time two single nucleotide polymorphisms (SNPs) in the regulatory region of genes encoding NADPH oxidase 4 (NOX4) and p22phox (CYBA) in NAFLD. METHODS: A total of 207 biopsy-proven NAFLD...

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Source

Identifiers

PMID: 30087027
DOI: 10.1016/j.hbpd.2018.06.005

Genes

CYBA
NOX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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