Article
The association between CYBA gene C242T variant and risk of metabolic syndrome.
European journal of clinical investigation - 1 Sept 2020
Pourgholi Leyla, Pourgholi Fatemeh, Ziaee Shayan, Goodarzynejad Hamidreza, Hosseindokht Maryam, Boroumand Mohammadali, Mandegary Ali
Abstract excerpt
BACKGROUND: Both inflammation and oxidative stress may contribute to pathogenesis of metabolic syndrome (MetS). The C242T polymorphism (rs4673) in the CYBA gene, as the main components of NAD (P) H oxidase, causes inter-individual variability in the enzyme activity. We aimed to investigate the association between this polymorphism with MetS and its components. METHODS: Two hundred nine patients with MetS and 232...
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