Article
Polymorphisms in NADPH oxidase CYBA gene modify the risk of ESRD in patients with chronic glomerulonephritis.
Renal failure - 1 Jan 2016
Zhou Hui, Chen Min, Zhu Ying, Wang Bing, Liu Xiao-ning, Zuo Zhi, Tang Feng-Ying
Abstract excerpt
End-stage renal disease (ESRD) was defined as start of renal replacement therapy or death due to kidney disease. However, death due to acute kidney injury was not included. It typically occurs when chronic renal failure progresses to a point where the kidneys are permanently functioning at less than 10% of their capacity. Oxidative stress (OS) plays a crucial role in ESRD. Nicotinamide adenine dinucleotide...
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