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Article

Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection.

Hepatology (Baltimore, Md.) - 1 Dec 2003

Hellier Simon, Frodsham Angela J, Hennig Branwen J W, Klenerman Paul, Knapp Suzanne, Ramaley Patricia, Satsangi Jack, Wright Mark, Zhang Lyna, Thomas Howard C, Thursz Mark, Hill Adrian V S

Abstract excerpt

The effect of host genetic variation on the outcome of hepatitis C virus (HCV) infection and its treatment is poorly understood. The chemokine receptors CCR5, CCR2, and CCR3 and their ligands, RANTES, MCP-1, MCP-2, and MIP-1alpha, are involved in the immune responses and the selective recruitment of lymphocytes to the liver in HCV infection. We studied 20 polymorphisms within these genes and investigated their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14647058
DOI: 10.1016/j.hep.2003.09.027

Genes

CCR5
CCR2
CCR3
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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