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Article

GREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approach.

Bioinformatics (Oxford, England) - 15 Aug 2015

Schmidt Ellen M, Zhang Ji, Zhou Wei, Chen Jin, Mohlke Karen L, Chen Y Eugene, Willer Cristen J

Abstract excerpt

MOTIVATION: The majority of variation identified by genome wide association studies falls in non-coding genomic regions and is hypothesized to impact regulatory elements that modulate gene expression. Here we present a statistically rigorous software tool GREGOR (Genomic Regulatory Elements and Gwas Overlap algoRithm) for evaluating enrichment of any set of genetic variants with any set of regulatory features....

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PMID: 25886982
DOI: 10.1093/bioinformatics/btv201
PMCID: PMC4612390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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