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Article

Gene-Gene Interactions Detection Using a Two-stage Model.

Journal of computational biology : a journal of computational molecular cell biology - 1 Jun 2015

Wang Zhanyong, Sul Jae Hoon, Snir Sagi, Lozano Jose A, Eskin Eleazar

Abstract excerpt

Genome-wide association studies (GWAS) have discovered numerous loci involved in genetic traits. Virtually all studies have reported associations between individual single nucleotide polymorphisms (SNPs) and traits. However, it is likely that complex traits are influenced by interaction of multiple SNPs. One approach to detect interactions of SNPs is the brute force approach which performs a pairwise association...

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Identifiers

PMID: 25871811
DOI: 10.1089/cmb.2014.0163
PMCID: PMC4449719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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