Article
Efficiently identifying significant associations in genome-wide association studies.
Journal of computational biology : a journal of computational molecular cell biology - 1 Oct 2013
Kostem Emrah, Eskin Eleazar
Abstract excerpt
Over the past several years, genome-wide association studies (GWAS) have implicated hundreds of genes in common disease. More recently, the GWAS approach has been utilized to identify regions of the genome that harbor variation affecting gene expression or expression quantitative trait loci (eQTLs). Unlike GWAS applied to clinical traits, where only a handful of phenotypes are analyzed per study, in eQTL studies,...
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