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Article

Fast association tests for genes with FAST.

PloS one - 1 Jan 2013

Chanda Pritam, Huang Hailiang, Arking Dan E, Bader Joel S

Abstract excerpt

UNLABELLED: Gene-based tests of association can increase the power of a genome-wide association study by aggregating multiple independent effects across a gene or locus into a single stronger signal. Recent gene-based tests have distinct approaches to selecting which variants to aggregate within a locus, modeling the effects of linkage disequilibrium, representing fractional allele counts from imputation, and...

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Identifiers

PMID: 23935874
DOI: 10.1371/journal.pone.0068585
PMCID: PMC3720833

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