Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detecting gene-gene interactions that underlie human diseases.

Nature reviews. Genetics - 1 Jun 2009

Cordell Heather J

Abstract excerpt

Following the identification of several disease-associated polymorphisms by genome-wide association (GWA) analysis, interest is now focusing on the detection of effects that, owing to their interaction with other genetic or environmental factors, might not be identified by using standard single-locus tests. In addition to increasing the power to detect associations, it is hoped that detecting interactions between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epistasis, Genetic
Share to Genes
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 19434077
DOI: 10.1038/nrg2579
PMCID: PMC2872761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detecting gene-gene interactions that underlie human diseases.PMID 19434077Read ↗

Analysis of gene-gene interactions.Semantic proximity Read ↗

Analysis of gene-gene interactions.Semantic proximity Read ↗

Analysis of gene-gene interactions.Semantic proximity Read ↗

Gene-Gene and Gene-Environment Interactions.Semantic proximity Read ↗

Genome-wide strategies for detecting multiple loci that influence complex diseases.Semantic proximity Read ↗

Comparative analysis of methods for detecting interacting loci.Semantic proximity Read ↗

Update on the State of the Science for Analytical Methods for Gene-Environment Interactions.Semantic proximity Read ↗

On epistasis: a methodological review for detecting gene-gene interactions underlying various types of phenotypic traits.Semantic proximity Read ↗

Statistical analysis of genetic interactions.Semantic proximity Read ↗

Analysis of Gene-Gene Interactions.Semantic proximity Read ↗

Gene--environment-wide association studies: emerging approaches.Semantic proximity Read ↗

Comparisons of power of statistical methods for gene-environment interaction analyses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.