Article
Association of TNF-alpha (-308 A/G) and IFN-gamma (+874 A/T) gene polymorphisms in response to spontaneous and treatment induced viral clearance in HCV infected multitransfused thalassemic patients.
Cytokine - 1 Jun 2018
Biswas Aritra, Gupta Nabyendu, Gupta Debanjali, Datta Abira, Firdaus Rushna, Chowdhury Prosanto, Bhattacharyya Maitreyee, Sadhukhan Provash C
Abstract excerpt
BACKGROUND: Multitransfused thalassemic individuals are at high risk of developing transfusion transmitted Hepatitis C virus (HCV) infection. The aim of the study was to correlate the effects of host cytokine single nucleotide polymorphisms of TNF-α (-308 A/G) and IFN-γ (+874 A/T) in spontaneous or IFN induced treatment response in the HCV infected thalassemic individuals. METHODS: A total of 427 HCV...
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