Article
Association with Spontaneous Hepatitis C Viral Clearance and Genetic Differentiation of IL28B/IFNL4 Haplotypes in Populations from Mexico.
PloS one - 1 Jan 2016
Gonzalez-Aldaco Karina, Rebello Pinho João R, Roman Sonia, Gleyzer Ketti, Fierro Nora A, Oyakawa Leticia, Ramos-Lopez Omar, Ferraz Santana Rubia A, Sitnik Roberta, Panduro Arturo
Abstract excerpt
AIM: To analyze the genetic heterogeneity of the Amerindian and admixed population (Mestizos) based on the IL28B (rs12979860, rs8099917) and IFNL4 (rs368234815) haplotypes, and their association with spontaneous clearance (SC) and liver damage in patients with hepatitis C infection from West Mexico. METHODS: A total of 711 subjects from West Mexico (181 Amerindians and 530 Mestizos) were studied for the...
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