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Article

IL28B polymorphisms influence stage of fibrosis and spontaneous or interferon-induced viral clearance in thalassemia patients with hepatitis C virus infection.

Haematologica - 1 May 2012

Di Marco Vito, Bronte Fabrizio, Calvaruso Vincenza, Capra Marcello, Borsellino Zelia, Maggio Aurelio, Renda Maria Concetta, Pitrolo Lorella, Lo Pinto Maria Carmela, Rizzo Michele, Fiorenza Flavia, Gerardi Calogera, Grimaudo Stefania, Di Cristina Antonietta, Levrero Massimo, Craxì Antonio

Abstract excerpt

BACKGROUND: Polymorphisms in the interleukin-28B are important determinants in the spontaneous and drug-induced control of hepatitis C virus infection. DESIGN AND METHODS: We assessed the association of rs8099917 and rs12979860 polymorphisms with spontaneous viral clearance, severity of liver fibrosis, and response to interferon-monotherapy in 245 thalassemia major patients with hepatitis C virus infection....

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Source

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Identifiers

PMID: 22180419
DOI: 10.3324/haematol.2011.050351
PMCID: PMC3342968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IL28B polymorphisms influence stage of fibrosis and spontaneous or interferon-induced viral clearance in thalassemia patients with hepatitis C virus infection.PMID 22180419Read ↗

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