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Article

The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes.

Frontiers in bioscience (Elite edition) - 1 Jun 2011

Moreno Maria de Ujue, San Jose Gorka, Fortuno Ana, Miguel-Carrasco Jose Luis, Beloqui Oscar, Diez Javier, Zalba Guillermo

Abstract excerpt

Oxidative stress is implicated in diabetes. The NADPH oxidases are the main source of superoxide in phagocytic and vascular cells, and p22phox is a key subunit. Genetic variants of CYBA, the human p22phox gene, associate with cardiovascular disease. We investigated the association of the A640G polymorphism with diabetes and its impact on phagocytic NADPH oxidase-dependent superoxide production and subclinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21622150
DOI: 10.2741/e347

Genes

CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes.PMID 21622150Read ↗

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CYBA gene variants as biomarkers for coronary artery disease.Semantic proximity Read ↗

The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.Semantic proximity Read ↗

A novel CYBA variant, the -675A/T polymorphism, is associated with essential hypertension.Semantic proximity Read ↗

C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils.Semantic proximity Read ↗

The -930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case-control study and gene-risk factors interactions.Semantic proximity Read ↗

Association of the C242T polymorphism in the NADPH oxidase p22 phox gene with carotid atherosclerosis in Slovenian patients with type 2 diabetes.Semantic proximity Read ↗

NAD(P)H oxidase p22phox Gene C242T polymorphism and lipoprotein oxidation.Semantic proximity Read ↗

Relationship between C242T polymorphism and arterial stiffness in an apparently healthy population.Semantic proximity Read ↗

CYBA C242T gene polymorphism and flow-mediated vasodilation in a population of young adults: the Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

Insight into the role of CYBA A640G and C242T gene variants and coronary heart disease risk. A case-control study.Semantic proximity Read ↗

Association of genetic variants in the promoter region of genes encoding p22phox (CYBA) and glutamate cysteine ligase catalytic subunit (GCLC) and renal disease in patients with type 1 diabetes mellitus.Semantic proximity Read ↗

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