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Article

Haplotype analysis of NAD(P)H oxidase p22 phox polymorphisms in end-stage renal disease.

Journal of human genetics - 1 Jan 2005

Doi Kent, Noiri Eisei, Nakao Akihide, Fujita Toshiro, Kobayashi Shuzo, Tokunaga Katsushi

Abstract excerpt

NAD(P)H oxidase is one of the most important sources of reactive oxygen species and has been demonstrated to be upregulated by angiotensin II in the kidney. Given the effect of angiotensin-converting enzyme inhibitors on the progression of both diabetic and non-diabetic renal disease, we hypothesized that the polymorphisms of NAD(P)H oxidase are associated with development of end-stage renal disease (ESRD). We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16215641
DOI: 10.1007/s10038-005-0310-4

Genes

CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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