Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-B27

21 Mar 2015

Abstract excerpt

Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown. Two broad theories most likely explain the role of HLA-B27 in AS pathogenesis. The first is based on the natural immunological function of HLA-B27 of presenting antigenic peptides to cytotoxic T cells. Thus, HLA-B27-restricted immune responses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to Rheumatoid Arthritis Research and Therapies
Share to Spondyloarthritis Studies and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25861975
DOI: 10.1146/annurev-immunol-032414-112110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-B27PMID 25861975Read ↗

HLA-B27 misfolding and ankylosing spondylitis.Semantic proximity Read ↗

Role of HLA-B27 in the pathogenesis of ankylosing spondylitisSemantic proximity Read ↗

What is the role of HLA-B27 in spondyloarthropathies?Semantic proximity Read ↗

Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27.Semantic proximity Read ↗

The immunobiology of HLA-B27: variations on a theme.Semantic proximity Read ↗

Peptides: the cornerstone of HLA‐B27 biology and pathogenetic role in spondyloarthritisSemantic proximity Read ↗

HLA-B27 and its pathogenic role.Semantic proximity Read ↗

Does HLA-B27 Status Influence Ankylosing Spondylitis Phenotype?Semantic proximity Read ↗

Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis.Semantic proximity Read ↗

Putative Pathobionts in HLA-B27-Associated SpondyloarthropathySemantic proximity Read ↗

Major histocompatibility genes and ankylosing spondylitis.Semantic proximity Read ↗

HLA-B27 and immunogenetics of spondyloarthropathies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.