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Article

Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27.

Frontiers in immunology - 1 Jan 2021

Thakur Amit Kumar, Luthra-Guptasarma Manni

Abstract excerpt

Ankylosing spondylitis (AS) belongs to a group of diseases, called spondyloarthropathies (SpA), that are strongly associated with the genetic marker HLA-B27. AS is characterized by inflammation of joints and primarily affects the spine. Over 160 subtypes of HLA-B27 are known, owing to high polymorphism. Some are strongly associated with disease (e.g., B*2704), whereas others are not (e.g., B*2709). Misfolding of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35082784
DOI: 10.3389/fimmu.2021.795053
PMCID: PMC8785436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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