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Article

Peptides: the cornerstone of HLA‐B27 biology and pathogenetic role in spondyloarthritis

15 May 2008

Abstract excerpt

The association of human leukocyte antigen (HLA)-B27 to ankylosing spondylitis is one of the strongest between a major histocompatibility complex molecule and a disease. Yet, the basis for this association remains unknown. Several hypotheses, each based on a particular feature of HLA-B27, guide much of the current research on the pathogenesis of this disease, but none has yet satisfactorily explained its...

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PMID: 18489433
DOI: 10.1111/j.1399-0039.2008.01051.x

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Peptides: the cornerstone of HLA‐B27 biology and pathogenetic role in spondyloarthritisPMID 18489433Read ↗

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Polymorphism of HLA-B27: 105 subtypes currently known.Semantic proximity Read ↗

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