Article
The immunobiology of HLA-B27: variations on a theme.
Current molecular medicine - 1 Feb 2004
Colbert Robert A
Abstract excerpt
In the thirty years since the initial discovery of a striking association between HLA-B27 and susceptibility to ankylosing spondylitis, numerous hypotheses have been proposed to explain the role of this molecule in the pathogenesis of spondyloarthropathies. In the past few years the focus has shifted from one centered largely on the physiological peptide-presenting function of HLA-B27, to include ideas based on...
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