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Article

HLA-B27 misfolding and ankylosing spondylitis.

Molecular immunology - 1 Jan 2014

Colbert Robert A, Tran Tri M, Layh-Schmitt Gerlinde

Abstract excerpt

Understanding how HLA-B27 contributes to the pathogenesis of spondyloarthritis continues to be an important goal. Current efforts are aimed largely on three areas of investigation; peptide presentation to CD8T cells, abnormal forms of the HLA-B27 heavy chain and their recognition by leukocyte immunoglobulin-like receptors on immune effector cells, and HLA-B27 heavy chain misfolding and intrinsic biological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23993278
DOI: 10.1016/j.molimm.2013.07.013
PMCID: PMC3857088

Genes

HSPA5
SYVN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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