Article
Epigenetic properties of white–opaque switching in <i>Candida albicans</i> are based on a self-sustaining transcriptional feedback loop
9 Aug 2006
Abstract excerpt
White-opaque switching in the human fungal pathogen Candida albicans is an alternation between two distinct types of cells, white and opaque. White and opaque cells differ in their appearance under the microscope, the genes they express, their mating behaviors, and the host tissues for which they are best suited. Each state is heritable for many generations, and switching between states occurs stochastically, at...
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