Article
H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes.
Nucleic acids research - 26 May 2015
Nadal-Ribelles Mariona, Mas Glòria, Millán-Zambrano Gonzalo, Solé Carme, Ammerer Gustav, Chávez Sebastián, Posas Francesc, de Nadal Eulàlia
Abstract excerpt
Chromatin remodeling is essential for proper adaptation to extracellular stimuli. The p38-related Hog1 SAPK is an important regulator of transcription that mediates chromatin remodeling upon stress. Hog1 targets the RSC chromatin remodeling complex to stress-responsive genes and rsc deficient cells display reduced induction of gene expression. Here we show that the absence of H3K4 methylation, either achieved by...
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