Article
Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis.
Molecular biology of the cell - 1 Feb 2004
O'Rourke Sean M, Herskowitz Ira
Abstract excerpt
The Saccharomyces cerevisiae high osmolarity glycerol (HOG) mitogen-activated protein kinase pathway is required for osmoadaptation and contains two branches that activate a mitogen-activated protein kinase (Hog1) via a mitogen-activated protein kinase kinase (Pbs2). We have characterized the roles of common pathway components (Hog1 and Pbs2) and components in the two upstream branches (Ste11, Sho1, and Ssk1) in...
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