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Article

Hos2p/Set3p deacetylase complex signals secretory stress through the Mpk1p cell integrity pathway.

Eukaryotic cell - 1 Jul 2008

Cohen T J, Mallory M J, Strich R, Yao T-P

Abstract excerpt

Perturbations in secretory function activate stress response pathways critical for yeast survival. Here we report the identification of the Hos2p/Set3p deacetylase complex (SET3C) as an essential component of the secretory stress response. Strains lacking core components of the Hos2p/Set3p complex exhibit hypersensitivity to secretory stress. Although not required for the unfolded protein response (UPR) and...

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Identifiers

PMID: 18487345
DOI: 10.1128/EC.00059-08
PMCID: PMC2446675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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