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Article

The Sch9 kinase is a chromatin-associated transcriptional activator of osmostress-responsive genes.

The EMBO journal - 11 Jul 2007

Pascual-Ahuir Amparo, Proft Markus

Abstract excerpt

The yeast Sch9 kinase has been implicated in the cellular adjustment to nutrient availability and in the regulation of aging. Here, we define a novel role for Sch9 in the transcriptional activation of osmostress inducible genes. Loss-of-function mutants sch9 are sensitive to hyperosmotic stress and show an impaired transcriptional response upon osmotic shock of several defense genes. We show that Sch9 is required...

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Source

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Identifiers

PMID: 17568771
DOI: 10.1038/sj.emboj.7601756
PMCID: PMC1914104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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