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Article

Cooperation between SAGA and SWI/SNF complexes is required for efficient transcriptional responses regulated by the yeast MAPK Slt2.

Nucleic acids research - 6 Sept 2016

Sanz Ana Belén, García Raúl, Rodríguez-Peña José Manuel, Nombela César, Arroyo Javier

Abstract excerpt

The transcriptional response of Saccharomyces cerevisiae to cell wall stress is mainly mediated by the cell wall integrity (CWI) pathway through the MAPK Slt2 and the transcription factor Rlm1. Once activated, Rlm1 interacts with the chromatin remodeling SWI/SNF complex which locally alters nucleosome positioning at the target promoters. Here we show that the SAGA complex plays along with the SWI/SNF complex an...

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Identifiers

PMID: 27112564
DOI: 10.1093/nar/gkw324
PMCID: PMC5009723

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Source receipt: pubmed, retrieved 7 Sept 2026.

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