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Article

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors.

European journal of epidemiology - 1 Jul 2015

Burgess Stephen, Scott Robert A, Timpson Nicholas J, Davey Smith George, Thompson Simon G

Abstract excerpt

Finding individual-level data for adequately-powered Mendelian randomization analyses may be problematic. As publicly-available summarized data on genetic associations with disease outcomes from large consortia are becoming more abundant, use of published data is an attractive analysis strategy for obtaining precise estimates of the causal effects of risk factors on outcomes. We detail the necessary steps for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25773750
DOI: 10.1007/s10654-015-0011-z
PMCID: PMC4516908

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CASR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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