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Article

Condensin HEAT subunits required for DNA repair, kinetochore/centromere function and ploidy maintenance in fission yeast.

PloS one - 1 Jan 2015

Xu Xingya, Nakazawa Norihiko, Yanagida Mitsuhiro

Abstract excerpt

Condensin, a central player in eukaryotic chromosomal dynamics, contains five evolutionarily-conserved subunits. Two SMC (structural maintenance of chromosomes) subunits contain ATPase, hinge, and coiled-coil domains. One non-SMC subunit is similar to bacterial kleisin, and two other non-SMC subunits contain HEAT (similar to armadillo) repeats. Here we report isolation and characterization of 21 fission yeast...

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PMID: 25764183
DOI: 10.1371/journal.pone.0119347
PMCID: PMC4357468

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