Article
A genetic screen for functional partners of condensin in fission yeast.
G3 (Bethesda, Md.) - 19 Feb 2014
Robellet Xavier, Fauque Lydia, Legros Pénélope, Mollereau Esther, Janczarski Stéphane, Parrinello Hugues, Desvignes Jean-Pierre, Thevenin Morgane, Bernard Pascal
Abstract excerpt
Mitotic chromosome condensation is a prerequisite for the accurate segregation of chromosomes during cell division, and the conserved condensin complex a central player of this process. However, how condensin binds chromatin and shapes mitotic chromosomes remain poorly understood. Recent genome-wide binding studies showing that in most species condensin is enriched near highly expressed genes suggest a conserved...
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